This second volume of the five-volume commentary by the renowned Buddhist scholar Geshe Lhundub Sopa focuses on the key Buddhist concepts of karma, or cause and effect, and dependent origination. Considered one of the finest living Buddhist scholars, Geshe Sopa provides commentaries essential for anyone interested in a sound understanding of Tibetan Buddhist practice and philosophy. Never has a book gone into such clear detail on karma and dependent origination--concepts which, despite many references in contemporary culture, are too often misunderstood. Here, Geshe Sopa starts from the beginning with a faithful reading of the Lamrim Chenmo and, in the end, leaves readers with the proper tools for incorporating core Buddhist concepts into their study, teaching, and practice.